Prozac and Zoloft are powerful prescription medications used to treat depression and other issues. The generic version of Prozac is fluoxetine, while the generic version of Zoloft is sertraline hydrochloride. Both drugs are selective serotonin reuptake inhibitors (SSRIs). Serotonin is a naturally occurring chemical that produces a feeling of well-being. These drugs work by influencing serotonin levels in your brain. By balancing chemicals in your brain, these drugs will likely improve your mood and appetite. They can also enhance your energy levels and help you sleep better. Both medications can reduce anxiety, fear, and compulsive behaviors. It's also used to treat obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (PMDD) and social anxiety disorder. Zoloft, an oral antidepressant pill made of compressed crystalline powder, is usually prescribed to first-time users in a 50-milligram-per-day dose for depression and PMDD and 25 milligrams per day for other disorders. Our bodies need time to adapt to the new normal created by taking a pill laced with sertraline that is designed to increase serotonin levels in the brain. Dosages can be increased with time and medical supervision up to 200 milligrams per day. Not only does this SSRI medication help the brain absorb serotonin into the blood stream more effectively, but it may actually change the makeup of the brain. It's also available in liquid form [source: RX List]. The brain needs new receptors to help absorb the additional serotonin; it builds and installs additional receptors -- a biological process that can take up to eight weeks. Within just a few hours of taking an SSRI for the first time, the levels of serotonin in the brain and bloodstream increase. So, even though Zoloft increases the levels of serotonin in our bodies nearly immediately, our brains aren't immediately equipped to absorb it [source: Crowe]. If, however, after six to eight weeks, Zoloft doesn't seem to be positively affecting your mood, anxiety -- or other condition for which it was prescribed -- it's time to alert your physician. Not every antidepressant will work the same for every person, and an estimated 50 percent of people who try an antidepressant will need to take a different brand or class before finding one that works for them. Lasix pharmacokinetics Tamoxifen retinopathy Buy cheap amoxil Feb 16, 2017. When a person starts taking Zoloft, it helps to know when to expect the medicine to kick in and start working. Symptoms may take a few weeks. Sertraline works by affecting the balance of chemicals in the brain. Specifically. Zoloft received an overall rating of 6 out of 10 stars from 1294 reviews. It works differently for everyone, and some people have different side effects than others. Sertraline belongs to a class of medications known as selective serotonin reuptake inhibitors (SSRIs). It is used to treat depression, panic disorder, and obsessive-compulsive disorder (OCD). Sertraline works by affecting the balance of chemicals in the brain. Specifically, it increases the level of a neurotransmitter called serotonin in the brain. Increased serotonin levels can help improve mood, reduce panic attacks, and treat OCD. Although improvements may occur earlier, the full response to the medication may not appear until after 4 weeks of treatment or longer. This medication may be available under multiple brand names and/or in several different forms. For a small amber or blue oval pill, Zoloft sure generates a lot of buzz -- and so do other members of its family of antidepressants. A study released in 2011 by the National Center for Health Statistics reports that from 2005 to 2008, one in 10 Americans age 12 and older took antidepressant medication, making antidepressants the third most commonly prescribed drug taken by Americans of all ages during and the No. Overall, the rate of antidepressant usage in the U. -- among all ages -- skyrocketed 400 percent between 19 [source: NCHS]. Zoloft -- also known by its generic name sertraline hydrochloride -- is a prescription antidepressant classified as a selective serotonin reuptake inhibitor (SSRI), as we mentioned. This class of antidepressants affects receptors in the brain that absorb serotonin. Serotonin -- 5-Hydroxytryptamine or 5-HT -- is a naturally occurring chemical found in intestines, blood platelets, certain cells and the brain. Serotonin is a derivative of tryptophan, a natural amino acid, and is concentrated in the midbrain and hypothalamus -- two areas responsible for mood, sleep and aggression. When there isn't enough serotonin, either because it is absorbed too quickly or in too great a quantity by the brain's neurons, depression can occur. Zoloft how it works Prozac vs. Zoloft What's the Difference? - Healthline, Zoloft - Uses, Side Effects, Interactions - Clomid hcg Zoloft Sertraline was primarily developed to regulate and balance chemicals in the brain and was commonly prescribed to treat depression, anxiety, and. How Zoloft Sertraline Works – in Layman's Terms -. Zoloft Reviews Everyday Health. How Do Antidepressants Work ? - YouTube. Sep 2, 2017. Zoloft sertraline is a selective serotonin reuptake inhibitor SSRI. Learn how it works to elevate mood and how it is used to treat conditions. Sertraline, sold under the trade name Zoloft among others, is an antidepressant of the selective. Sertraline is believed to work by increasing serotonin effects in the brain. Sertraline was approved for medical use in the United States in 1991. For a small amber or blue oval pill, Zoloft sure generates a lot of buzz -- and so do other members of its family of antidepressants. A study released in 2011 by.